
I just read another interesting article on the anti-inflammatory drugs being used to replace some of the ones currently in question.
I think this would be a great time for everyone to sit back and explore the relative risk and benefits posed by all medications. I have young, healthy patients at little or no risk of heart or other vascular disease who believe that it is a good idea for them to take an aspirin a day. I really don't know of any conclusive proof of any benefit to this group of patients. I do know that they remain at a somewhat greater risk of GI ulcer from aspirin therapy. They ask, "Well, it can't hurt...can it?" I have to tell them while the risk is low, it could hurt (even be life-threatening) and the therapy really offers no benefit to them.
This is different than someone taking a low-dose COX-2 inhibitor with a (potentially obvious) benefit of decreased pain and increased mobility and a low (depending on the patient type) risk of heart attack. The patient and physician ought to be able to weigh these decisions at the time of prescription. I don't get to do that with over-the-counter treatments unless my patient tells me about it, assuming that I see that patient on a semi-regular basis.





